王晓杰 博士,山东大学基础医学院助理研究员
山东济南文化西路44号
电话 : 0531-88382036
E-mail: wangxiaojie@sdu.edu.cn
科研经历:
2017.10-2018.10,Brigham and Women's Hospital,访问学者
2015.7-至今 山东大学基础医学院助理研究员
2010.9-2015.06 山东大学医学院博士
研究领域:
糖尿病肾病,肾脏免疫药理
论文发表情况:
1. Wang Xiaojie, Li Jiang, Yi Fan. HDAC4 Selectively Contributes to Podocyte Injury in Diabetic Nephropathy. Kidney International. 2014 Oct; (SCI IF:8.52)
This article was honored by an editorial commentary:
本篇文章被选为编辑特邀评述
Wei Q, Dong Z. HDAC4 blocks autophagy to trigger podocyte injury: non-epigenetic action in diabetic nephropathy. Kidney Int. 2014 Oct; 86(4):666-8. doi: 10.1038/ki.2014.142.
This article was highlighted in that issue:
本篇文章被选为本期重点推荐文章
http://www.nature.com/ki/journal/v86/n4/pdf/ki2014307a.pdf
2. Wang Xiaojie, Yi Fan, Implication of Pattern-recognition Receptors in Cardiovascular Diseases. Antioxid Redox Sign 2014 Nov 11. (SCI IF:7.71)
3. Wang Xiaojie, Wei XB, Pang Q, Yi Fan. Histone deacetylases and their inhibitors: molecular mechanisms and therapeutic implications in diabetes mellitus, Acta Pharmaceutica Sinica B 2012 2(4):387-395
4. Shang Jin, Wan Qiang, Wang Xiaojie, Duan Yiqi, Yi Fan. Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy. Free Radic Biol Med. 2015 Feb; (SCI IF:5.71)
5. Du P, Fan B, Han H, Zhen J, Shang J, Wang Xiaojie, Li X, Shi W, Tang W, Bao C, Wang Z, Zhang Y, Zhang B, Wei X, Yi Fan. NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney International. 2013 Aug; (SCI IF:8.52)
6. Li X, Li FL, Chu YL, Wang Xiaojie, Zhang HY, HU YY, Zhang Y, Wang ZY, Jian WC, Zhang XM, Yi Fan. NOD2 Deficiency Protects against Cardiac Remodeling after Myocardial Infarction in Mice. Cell Physiol Biochem 2013 Dec ( SCI IF: 3.48)
承担课题情况:
1. 国家自然科学基金青年基金项目,81600570, GPR124在糖尿病肾病足细胞损伤中的保护作用及分子机制, 2017/01-2019/12,17万元,在研,主持
2. 中国博士后面上项目一等资助,GPR124在糖尿病肾病中的作用及对自噬的调控机制研究, 2016/0-2018/05,8万元,在研,主持
3. 国家自然科学基金重大研究计划,91642204,模式识别受体介导的足细胞免疫调控在肾小球疾病中的作用,2017/01-2020/12.31,200万元,在研,参与。
荣誉和奖项:
山东省优秀博士学位论文 2016
山东大学校长奖学金,2014
山东省药理学年会“优秀药理学工作者”称号,2014